One the guys I hunted with in Oregon used a 338-378. He was part of our group that spent 23 days hunting in Montana just before I moved to Idaho. I saw him take a nice whitetail at over 900 yards. That was John's goal - to be a long range hunter. So my question is what is going to be the purpose of a 30-378? What is your goal with the 30-378? Nothing wrong for just wanting the biggest 30 commercially available. From my research, I think if it is to be a long-range shooter, the 338 in several renditions will out perform the 30 cal. This is coming from a guy who shoots a 300 RUM. I wanted a 300 RUM again for several reasons. One was I never tamed the beast the first time I owned one. Second, I really like hunting desert mule deer. It is nice having a flat shooting rifle when there can be 600-700 yard shots. I like to keep them under 500 if at all possible. I must admit I just like shooting boomers!!